Cusabio Polyclonal Antibodies
PLEKHO1 Antibody, HRP conjugated | CSB-PA706633LB01HU
- SKU:
- CSB-PA706633LB01HU
- Availability:
- 3 to 7 Working Days
Description
PLEKHO1 Antibody, HRP conjugated | CSB-PA706633LB01HU | Cusabio
PLEKHO1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: PLEKHO1
Aliases: Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein), PLEKHO1, CKIP1 OC120
Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) . May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2) . Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: Q53GL0
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Pleckstrin homology domain-containing family O member 1 protein (143-404AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Signal transduction