PLEKHO1 Antibody, Biotin conjugated | CSB-PA706633LD01HU

PLEKHO1 Antibody, Biotin conjugated | CSB-PA706633LD01HU | Cusabio

PLEKHO1 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PLEKHO1

Aliases: Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein), PLEKHO1, CKIP1 OC120

Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP) . May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2) . Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q53GL0

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Pleckstrin homology domain-containing family O member 1 protein (143-404AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction