PKM Monoclonal Antibody | CSB-MA018072A1m
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PKM Monoclonal Antibody | CSB-MA018072A1m | Cusabio
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Product Type: Monoclonal Antibody
Target Name: PKM
Aliases: CTHBP antibody; Cytosolic thyroid hormone-binding protein antibody; KPYM_HUMAN antibody; OIP-3 antibody; Opa-interacting protein 3 antibody; p58 antibody; pkm antibody; PKM1 antibody; PKM2 antibody; Pyruvate kinase 2/3 antibody; Pyruvate kinase muscle isozyme antibody; Pyruvate kinase PKM antibody; THBP1 antibody; Thyroid hormone-binding protein 1 antibody; Tumor M2-PK antibody
Relevance: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Clone Number: 4C8E12
Uniport ID: P14618
Alternatives To SCBT: #N/A
Host Species: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant Human Pyruvate kinase PKM protein (2-531AA)
Immunogen Species: Human
Applications: ELISA, WB, IHC, IF, FC, IP
Tested Applications: ELISA, WB, IHC, IF, FC, IP; Recommended dilution: WB: 1:4000-1:512000, IHC: 1:500-1:1000, IF: 1:150-1:300, FC: 1:50-1:100, IP: 1µl-4µl
Purification Method: >95%, Protein G purified
Dilution Ratio1: WB:1:4000-1:512000
Dilution Ratio2: IHC:1:500-1:1000
Dilution Ratio3: IF:1:150-1:300
Dilution Ratio4: FC:1:50-1:100
Dilution Ratio5: IP:1µl-4µl
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Immunology
Research Areas: Immunology