PKM Monoclonal Antibody | CSB-MA018072A1m

PKM Monoclonal Antibody | CSB-MA018072A1m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: PKM

Aliases: CTHBP antibody; Cytosolic thyroid hormone-binding protein antibody; KPYM_HUMAN antibody; OIP-3 antibody; Opa-interacting protein 3 antibody; p58 antibody; pkm antibody; PKM1 antibody; PKM2 antibody; Pyruvate kinase 2/3 antibody; Pyruvate kinase muscle isozyme antibody; Pyruvate kinase PKM antibody; THBP1 antibody; Thyroid hormone-binding protein 1 antibody; Tumor M2-PK antibody

Relevance: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number: 4C8E12

Uniport ID: P14618

Alternatives To SCBT: #N/A

Host Species: Mouse

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Pyruvate kinase PKM protein (2-531AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF, FC, IP

Tested Applications: ELISA, WB, IHC, IF, FC, IP; Recommended dilution: WB: 1:4000-1:512000, IHC: 1:500-1:1000, IF: 1:150-1:300, FC: 1:50-1:100, IP: 1µl-4µl

Purification Method: >95%, Protein G purified

Dilution Ratio1: WB:1:4000-1:512000

Dilution Ratio2: IHC:1:500-1:1000

Dilution Ratio3: IF:1:150-1:300

Dilution Ratio4: FC:1:50-1:100

Dilution Ratio5: IP:1µl-4µl

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology