Phospho-SMAD2 (Ser250) Antibody | CSB-PA788461

Phospho-SMAD2 (Ser250) Antibody | CSB-PA788461 | Cusabio

Phospho-SMAD2 (Ser250) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: SMAD2

Aliases: JV18-1; MADH2; Mad-related protein 2; Mothers against DPP homolog 2;

Background:

Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD) . May act as a tumor suppressor in colorectal carcinoma.

Fransvea E, Mazzocca A, Antonaci S, Giannelli G (2009) Hepatology 49, 839-50 . Funaba M, Zimmerman CM, Mathews LS (2002) J Biol Chem 277, 41361-8. Kretzschmar M, Doody J, Timokhina I, Massagu篓 J (1999) Genes Dev 13, 804-16 .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q15796

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of serine250 (E-L-S (p) -P-T) derived from Human Smad2 .

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Epigenetics & Nuclear Signaling;Cancer;Signal transduction;Stem cells