Phospho-MAP3K5 (Ser966) Antibody | CSB-PA009239

Phospho-MAP3K5 (Ser966) Antibody | CSB-PA009239 | Cusabio

Phospho-MAP3K5 (Ser966) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MAP3K5

Aliases: ASK-1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5

Background:

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

Zhang W, et al. (2005) J Biol Chem. 280 (19) : 19036-19044.
Fujii K, et al. (2004) Oncogene. 23 (29) :5099-5104.
Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12; 279 (11) : 10442-10449.
Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96 (15) : 8511-8515.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99683

Host Species: Rabbit

Species Reactivity: Human, Mouse, Monkey

Immunogen: Peptide sequence around phosphorylation site of serine 966 (S-I-S (p) -L-P) derived from Human ASK1.

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cardiovascular;Cell biology