Phospho-ICAM1 (Tyr512) Antibody | CSB-PA928596

Phospho-ICAM1 (Tyr512) Antibody | CSB-PA928596 | Cusabio

Phospho-ICAM1 (Tyr512) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ICAM1

Aliases: ICA1; ICAM1;

Background:

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2) . During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Greenwood J, et al. (2003) J Immunol; 171 (4) :2099-2108.
Zhou Z, et al. (2005) Eur J Pharmacol; 513 (1-2) :1-8.
Chen YH, et al. (2001) J Cell Biochem; 82 (3) :512-521
 

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P05362

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Peptide sequence around phosphorylation site of tyrosine 512 (K-K-Y (p) -R-L) derived from Human ICAM-1.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:1000

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cardiovascular;Immunology;Stem cells