Phospho-Histone H3.3 (T3) Antibody | CSB-RA010109A03phHU
- 3 to 7 Working Days
Phospho-Histone H3.3 (T3) Antibody | CSB-RA010109A03phHU | Cusabio
Phospho-Histone H3.3 (T3) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Antibody Type: Recombinant Antibody
Target Names: H3F3A
Aliases: Histone H3.3, H3F3A, H3.3A, H3F3, PP781, AND, H3F3B, H3.3B
Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Isotype: Rabbit IgG
Clone Number: 28H4
Uniport ID: P84243
Modified: Epigenetics and Nuclear Signaling
Species Reactivity: Human, Mouse
Immunogen: A synthesized peptide
Tested Applications: ELISA, WB, ICC, FC; Recommended dilution: WB:1:500-1:5000, ICC:1:50-1:500
Purification Method: Affinity-chromatography
Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.