Phospho-EGFR (Tyr1197) Antibody | CSB-PA049634

Phospho-EGFR (Tyr1197) Antibody | CSB-PA049634 | Cusabio

Phospho-EGFR (Tyr1197) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: EGFR

Aliases: ERBB1; Receptor protein-tyrosine kinase ErbB-1; kinase EGFR

Background: Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

Corbalan-Garcia S, et al. (1996) Mol Cell Biolt; 16 (10) : 5674-5682
Kanner SB, et al. (1991) Mol Cell Biol; 11 (2) : 713-720
Wu TT, et al. (1998) Mol Biol Cell; 9 (7) : 1661-1674
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Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P00533

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of tyrosine 1197 (A-E-Y (p) -L-R) derived from Human EGFR.

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Signal transduction