Cusabio Polyclonal Antibodies
Phospho-CREB1 (Ser129) Antibody | CSB-PA122114
- 3 to 7 Working Days
Phospho-CREB1 (Ser129) Antibody | CSB-PA122114 | Cusabio
Phospho-CREB1 (Ser129) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: CREB1
Aliases: CREB-1; CREB1;
Background: This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.
Chrystelle V. Garat, et al. (2006) Mol. Cell. Biol ; 26: 4934 - 4948.
Lilah Rothem, et al. (2004) Mol. Pharmacol ; 66: 1536 - 1543.
Darren R. Tyson, et, al. (2002) Endocrinology; 143: 674.
Kyung-Woo Park, et al. (2003) Arterioscler. Thromb. Vasc. Biol ; 23: 1364.
Uniport ID: P16220
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of serine 129 (I-L-S (p) -R-R) derived from Human CREB.
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3: IHC:1:50-1:100
Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling;Immunology