Phospho-BCAR1 (Tyr410) Antibody | CSB-PA975216

Phospho-BCAR1 (Tyr410) Antibody | CSB-PA975216 | Cusabio

Phospho-BCAR1 (Tyr410) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: BCAR1

Aliases: BCAR1; CRKAS; CRK-ASSOCIATED SUBSTRATE;

Background:

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535.
Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863.
Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189.
Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P56945

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Peptide sequence around phosphorylation site of tyrosine 410 (G-V-Y (p) -A-V) derived from Human p130 Cas .

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:1000

Dilution Ratio3: IHC:1:50-1:100

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Signal transduction