Cusabio Polyclonal Antibodies
Phospho-BAD (Ser91/128) Antibody | CSB-PA148354
- SKU:
- CSB-PA148354
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
Phospho-BAD (Ser91/128) Antibody | CSB-PA148354 | Cusabio
Phospho-BAD (Ser91/128) Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: BAD
Aliases: BAD; BBC6; BCL2L8; Bcl- XL/Bcl-2 associated death promoter;
Background:
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Wang H.-G., Cell 87:629-638 (1996) .
Ottilie S., J. Biol. Chem. 272:30866-30872 (1997) .
The MGC Project Team, Genome Res. 14:2121-2127 (2004) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q92934
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of Serine 91 (E-P-S (p) -P-F) derived from Human BAD or Serine 128 (E-P-S (p) -P-F) derived from Mouse BAD.
Immunogen Species: Human
Applications: ELISA, WB, IHC
Tested Applications: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100
Purification Method: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3: IHC:1:50-1:100
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Cell Biology
Research Areas: Cancer;Cell biology;Metabolism