Cusabio Polyclonal Antibodies
PDK1 Antibody, HRP conjugated | CSB-PA613584LB01HU
- SKU:
- CSB-PA613584LB01HU
- Availability:
- 3 to 7 Working Days
Description
PDK1 Antibody, HRP conjugated | CSB-PA613584LB01HU | Cusabio
PDK1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: PDK1
Aliases: [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1), PDK1, PDHK1
Background: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
Isotype: IgG
Conjugate: HRP
Clonality: Polyclonal
Uniport ID: Q15118
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 1, mitochondrial protein (294-432AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Cancer;Metabolism;Signal transduction