PDE9A Antibody, Biotin conjugated | CSB-PA527985LD01HU

PDE9A Antibody, Biotin conjugated | CSB-PA527985LD01HU | Cusabio

PDE9A Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PDE9A

Aliases: High affinity cGMP-specific 3', 5'-cyclic phosphodiesterase 9A (EC 3.1.4.35), PDE9A

Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814) . Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991) . Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable) . In brain, involved in cognitive function, such as learning and long-term memory (By similarity) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: O76083

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human High affinity cGMP-specific 3', 5'-cyclic phosphodiesterase 9A protein (426-533AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction