PARP2 Antibody, HRP conjugated | CSB-PA866224LB01HU

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PARP2 Antibody, HRP conjugated | CSB-PA866224LB01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: PARP2

Aliases: Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (NAD (+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2), PARP2, ADPRT2 ADPRTL2

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768) . This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (PubMed:10364231) . Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity (PubMed:28190768) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q9UGN5

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Poly [ADP-ribose] polymerase 2 protein (14-149AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling

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