PAN2 Antibody, HRP conjugated | CSB-PA681391LB01HU

PAN2 Antibody, HRP conjugated | CSB-PA681391LB01HU | Cusabio

PAN2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: PAN2

Aliases: PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly (A) -specific ribonuclease) (Poly (A) -nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2), PAN2, KIAA0710 USP52

Background: Catalytic subunit of the poly (A) -nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly (A) tails of RNA when the poly (A) stretch is bound by poly (A) -binding protein (PABP), which is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q504Q3

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human PAB-dependent poly (A) -specific ribonuclease subunit PAN2 protein (628-908AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling