P4HB Antibody, HRP conjugated | CSB-PA823188YB01DXU
- 3 to 7 Working Days
P4HB Antibody, HRP conjugated | CSB-PA823188YB01DXU | Cusabio
P4HB Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: P4HB
Aliases: Protein disulfide-isomerase (PDI) (EC 188.8.131.52) (Prolyl 4-hydroxylase subunit beta) (p58), P4HB, PDIA1
Background: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity) . May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
Uniport ID: Q8R4U2
Host Species: Rabbit
Species Reactivity: Cricetulus griseus
Immunogen: Recombinant Cricetulus griseus Protein disulfide-isomerase protein (20-509AA)
Immunogen Species: Cricetulus griseus
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others