OCRL Antibody | CSB-PA016267LA01HU

OCRL Antibody | CSB-PA016267LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: OCRL

Aliases: Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein), OCRL, INPP5F OCRL1

Background: Converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698) . May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4, 5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q01968

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Inositol polyphosphate 5-phosphatase OCRL-1 protein (121-271AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:200-1:500

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Metabolism;Signal transduction