NKX3-1 Antibody | CSB-PA143729

NKX3-1 Antibody | CSB-PA143729 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: NKX3-1

Aliases: Homeobox protein Nkx-3.1; NKX31; NKX3A;

Background: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464.
Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017.
Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173.
Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q99801

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from N-terminal of human NKX3.

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC;IHC:1:50-1:100

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:50-1:100

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling