NGEF Antibody, Biotin conjugated | CSB-PA850809LD01HU

NGEF Antibody, Biotin conjugated | CSB-PA850809LD01HU | Cusabio

NGEF Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: NGEF

Aliases: Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor), NGEF

Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q8N5V2

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Ephexin-1 protein (495-710AA)

Immunogen Species: Homo sapiens (Human)

Applications: ELISA

Tested Applications: ELISA

Purification Method: Antigen Affinity Purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Neuroscience;Signal transduction