Cusabio Polyclonal Antibodies
NF2 Antibody, HRP conjugated | CSB-PA015741LB01HU
- 3 to 7 Working Days
NF2 Antibody, HRP conjugated | CSB-PA015741LB01HU | Cusabio
NF2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: NF2
Aliases: Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin), NF2, SCH
Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-DCAF1/DCAF1 E3 ubiquitin-protein ligase complex.
Uniport ID: P35240
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Merlin protein (230-414AA)
Immunogen Species: Human
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Neuroscience
Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Cancer;Signal transduction