NBPF1/NBPF9/NBPF10/NBPF12/NBPF14/NBPF15/NBPF16/NBPF20 Antibody | CSB-PA279287

NBPF1/NBPF9/NBPF10/NBPF12/NBPF14/NBPF15/NBPF16/NBPF20 Antibody | CSB-PA279287 | Cusabio

NBPF1/NBPF9/NBPF10/NBPF12/NBPF14/NBPF15/NBPF16/NBPF20 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: NBPF12/NBPF10/NBPF1/NBPF9

Aliases: NBPFC; neuroblastoma breakpoint family; 12;

Background:

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.

Gregory S.G., Nature 441:315-321 (2006) .
Mei G., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q5TAG4/Q6P3W6/Q5SXJ2/Q3BBV0/Q3BBW0/Q3B

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human NBPF1/9/10/12/14/15/16/20.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

Dilution Ratio3:

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Others

Research Areas: Others