NAT10 Antibody, HRP conjugated | CSB-PA863939LB01HU

NAT10 Antibody, HRP conjugated | CSB-PA863939LB01HU | Cusabio

NAT10 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: NAT10

Aliases: RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10), NAT10, ALP KIAA1709

Background: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25653167) . Catalyzes the formation of N (4) -acetylcytidine (ac4C) at positions 1337 and 1842 in 18S rRNA (By similarity) . Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25653167) . Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity) . Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167) . Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:14592445, PubMed:17631499, PubMed:18082603, PubMed:19303003) .

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q9H0A0

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human RNA cytidine acetyltransferase protein (909-1025AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cell biology;Signal transduction