Cusabio Polyclonal Antibodies
MYD88 Antibody, Biotin conjugated | CSB-PA859945LD01HU
- 3 to 7 Working Days
MYD88 Antibody, Biotin conjugated | CSB-PA859945LD01HU | Cusabio
MYD88 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: MYD88
Aliases: Myeloid differentiation primary response protein MyD88, MYD88
Background: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
Uniport ID: Q99836
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Myeloid differentiation primary response protein MyD88 protein (1-282AA)
Immunogen Species: Human
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Cardiovascular;Immunology;Signal transduction