MMP11 Antibody | CSB-PA974106

MMP11 Antibody | CSB-PA974106 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MMP11

Aliases: Matrix metallopeptidase 11 (stromelysin 3)

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P24347

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthetic peptide of human MMP11

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;ELISA:1:1000-1:5000, WB:1:500-1:2000

Purification Method: Antigen affinity purification

Dilution Ratio1: ELISA:1:1000-1:5000

Dilution Ratio2: WB:1:500-1:2000

Dilution Ratio3:

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Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cancer;Cardiovascular;Cell biology;Signal transduction