MLKL Antibody | CSB-PA850851LA01HU

MLKL Antibody | CSB-PA850851LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MLKL

Aliases: Mixed lineage kinase domain-like protein (hMLKL), MLKL

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q8NB16

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Mixed lineage kinase domain-like protein (1-471AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Cancer;Signal transduction