MLF1 Antibody | CSB-PA583476

MLF1 Antibody | CSB-PA583476 | Cusabio

MLF1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MLF1

Aliases: Myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1;

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Yoneda-Kato N., Oncogene 12:265-275 (1996) [PubMed: 8570204].
Hanissian S.H., Oncogene 23:3700-3707 (2004) [PubMed: 15116101].
Yoneda-Kato N., EMBO J. 24:1739-1749 (2005) [PubMed: 15861129].

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P58340

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Synthesized peptide derived from internal of human MLF1.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Cardiovascular;Cell biology;Tags & Cell Markers;Stem cells