MFN2 Antibody, HRP conjugated | CSB-PA013756LB01HU

MFN2 Antibody, HRP conjugated | CSB-PA013756LB01HU | Cusabio

MFN2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MFN2

Aliases: Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2), MFN2, CPRP1 KIAA0214

Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) . Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: O95140

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Mitofusin-2 protein (61-158AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Tags & Cell Markers

Research Areas: Neuroscience;Cancer;Cell biology;Tags & Cell Markers;Metabolism;Signal transduction