MESP2 Antibody | CSB-PA613150ESR1HU

MESP2 Antibody | CSB-PA613150ESR1HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MESP2

Aliases: Mesoderm posterior protein 2 (Class C basic helix-loop-helix protein 6) (bHLHc6), MESP2, BHLHC6 SCDO2

Background: Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q0VG99

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Mesoderm posterior protein 2 protein (218-397AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: Antigen Affinity Purified

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Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Neuroscience

Research Areas: Epigenetics & Nuclear Signaling;Neuroscience;Developmental biology