MBD3 Antibody | CSB-PA013532LA01HU

MBD3 Antibody | CSB-PA013532LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MBD3

Aliases: Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3), MBD3

Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O95983

Host Species: Rabbit

Species Reactivity: Human, Mouse

Immunogen: Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling