Cusabio Polyclonal Antibodies
MAPK14 (Ab-182) Antibody | CSB-PA112086
- SKU:
- CSB-PA112086
- Availability:
- 3 to 7 Working Days
- Size:
- 100ul
Description
MAPK14 (Ab-182) Antibody | CSB-PA112086 | Cusabio
MAPK14 (Ab-182) Antibody is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to info@gentaur.com.
Product Type: Polyclonal Antibody
Target Names: MAPK14
Aliases: MAPK2; MAPKAPK-2; MAPKAPK2
Background: Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Ming Zheng, et al. (2005) The FASEB Journal. 19: 109-111
Bernt van den et al. (2001) Blink Immunology, 166: 582-587
Arshad Rahman, et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024
Osamu Yoshino, et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q16539
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around aa. 180~184 (T-G-Y-V-A) derived from Human P38 MAPK.
Immunogen Species: Human
Applications: ELISA, WB
Tested Applications: ELISA, WB;WB:1:500-1:1000
Purification Method: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:500-1:1000
Dilution Ratio3:
Dilution Ratio4:
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Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form: liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Signal Transduction
Research Areas: Cancer;Immunology;Signal transduction