MAP3K13 Antibody | CSB-PA029472

MAP3K13 Antibody | CSB-PA029472 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MAP3K13

Aliases: Mitogen-activated protein kinase kinase kinase 13; EC 2.7.11.25; Mixed lineage kinase; MLK; Leucine zipper-bearing kinase

Background: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Sakuma H., J. Biol. Chem. 272:28622-28629 (1997) .
Schultz S.J., Cell Growth Differ. 4:821-830 (1993) .
Ikeda A., FEBS Lett. 488:190-195 (2001) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: O43283

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Synthesized peptide derived from internal of human M3K13.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction