MAN1B1 Antibody | CSB-PA217897

MAN1B1 Antibody | CSB-PA217897 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: MAN1B1

Aliases: Endoplasmic reticulum mannosyl-oligosaccharide 1; 2-alpha-mannosidase; EC=3.2.1.113; ER alpha-1; 2-mannosidase

Background: Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1, 2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.

Tremblay L.O., Glycobiology 9:1073-1078 (1999) [PubMed: 10521544].
Gonzalez D.S., J. Biol. Chem. 274:21375-21386 (1999) [PubMed: 10409699].
Clark H.F., Genome Res. 13:2265-2270 (2003) [PubMed: 12975309].

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9UKM7

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human MAN1B1.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Tags & Cell Markers

Research Areas: Tags & Cell Markers