MAGEC2 Antibody | CSB-PA574003

MAGEC2 Antibody | CSB-PA574003 | Cusabio

MAGEC2 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: MAGEC2

Aliases: Cancer/testis antigen 10; CT10; HCA587; hepatocellular cancer antigen 587; Hepatocellular carcinoma-associated antigen 587

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Gure A.O., Int. J. Cancer 85:726-732 (2000) [PubMed: 10699956].
Lucas S., Int. J. Cancer 87:55-60 (2000) [PubMed: 10861452].
Wang Y., J. Immunol. 169:1102-1109 (2002) [PubMed: 12097419].

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9UBF1

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human MAGEC2.

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:3000

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:3000

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cancer

Research Areas: Cancer;Immunology