LILRB4 Antibody | CSB-PA297929

LILRB4 Antibody | CSB-PA297929 | Cusabio

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Product Type: Polyclonal Antibody

Target Names: LILRB4

Aliases: Leukocyte immunoglobulin-like receptor subfamily B member 4 ; Leukocyte immunoglobulin-like receptor 5; LIR-5; Immunoglobulin-like transcript 3; ILT-3

Background: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Arm J.P., J. Immunol. 159:2342-2349 (1997) .
Borges L., J. Immunol. 159:5192-5196 (1997) .
Liu W.R., Immunogenetics 51:659-669 (2000) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q8NHJ6

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Synthesized peptide derived from internal of human LILRB4.

Immunogen Species: Human

Applications: ELISA, IF

Tested Applications: ELISA, IF;IF:1:100-1:500

Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IF:1:100-1:500

Dilution Ratio3:

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Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Epigenetics & Nuclear Signaling;Cardiovascular;Immunology