KSR2 Antibody, HRP conjugated | CSB-PA012696LB01HU

KSR2 Antibody, HRP conjugated | CSB-PA012696LB01HU | Cusabio

KSR2 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: KSR2

Aliases: Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1), KSR2

Background: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro) . Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro) . Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q6VAB6

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction