KRT17 Antibody, Biotin conjugated | CSB-PA012516LD01BO
- 3 to 7 Working Days
KRT17 Antibody, Biotin conjugated | CSB-PA012516LD01BO | Cusabio
KRT17 Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.
Online Order Payment is possible or send quotation to firstname.lastname@example.org.
Product Type: Polyclonal Antibody
Target Names: KRT17
Aliases: Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17), KRT17
Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Uniport ID: A1L595
Host Species: Rabbit
Species Reactivity: Bovine
Immunogen: Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)
Immunogen Species: Bovine
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others