KIDINS220 Antibody, FITC conjugated | CSB-PA012306LC01HU

KIDINS220 Antibody, FITC conjugated | CSB-PA012306LC01HU | Cusabio

KIDINS220 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: KIDINS220

Aliases: Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein), KIDINS220, ARMS KIAA1250

Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF) -induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity) . Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Isotype: IgG

Conjugate: FITC

Clonality: Polyclonal

Uniport ID: Q9ULH0

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cardiovascular

Research Areas: Neuroscience;Cardiovascular;Signal transduction