KEAP1 Antibody, HRP conjugated | CSB-PA012147LB01HU

KEAP1 Antibody, HRP conjugated | CSB-PA012147LB01HU | Cusabio

KEAP1 Antibody, HRP conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: KEAP1

Aliases: Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19), KEAP1, INRF2 KIAA0132 KLHL19

Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

Isotype: IgG

Conjugate: HRP

Clonality: Polyclonal

Uniport ID: Q14145

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Kelch-like ECH-associated protein 1 protein (1-624AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling