KDM8 Antibody | CSB-PA839789LA01HU

KDM8 Antibody | CSB-PA839789LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: KDM8

Aliases: JmjC domain-containing protein 5 (EC 1.14.11.27) (EC 3.4.-.-) (Jumonji domain-containing protein 5) (Lysine-specific demethylase 8), KDM8, JMJD5

Background: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q8N371

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human JmjC domain-containing protein 5 protein (151-380AA)

Immunogen Species: Human

Applications: ELISA, IHC

Tested Applications: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: IHC:1:20-1:200

Dilution Ratio3:

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling