ITPK1 Antibody | CSB-PA613412ESR2HU

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SKU:
CSB-PA613412ESR2HU
Availability:
3 to 7 Working Days
  • ITPK1 Antibody
  • Western blot<br />
 All lanes: ITPK1 antibody at 3.58µg/ml<br />
 Lane 1: Hela whole cell lysate<br />
 Lane 2: HepG2 whole cell lysate<br />
 Lane 3: A431 whole cell lysate<br />
 Secondary<br />
 Goat polyclonal to rabbit IgG at 1/10000 dilution<br />
 Predicted band size: 46, 36 kDa<br />
 Observed band size: 46 kDa<br />
  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA613412ESR2HU at dilution of 1:100
  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA613412ESR2HU at dilution of 1:100
$276.00 - $380.52

Description

ITPK1 Antibody | CSB-PA613412ESR2HU | Cusabio

ITPK1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: ITPK1

Aliases: Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1, 3, 4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins (1, 3, 4) P (3) 5/6-kinase) (EC 2.7.1.159), ITPK1

Background: Kinase that can phosphorylate various inositol polyphosphate such as Ins (3, 4, 5, 6) P4 or Ins (1, 3, 4) P3. Phosphorylates Ins (3, 4, 5, 6) P4 at position 1 to form Ins (1, 3, 4, 5, 6) P5. This reaction is thought to have regulatory importance, since Ins (3, 4, 5, 6) P4 is an inhibitor of plasma membrane Ca (2+) -activated Cl (-) channels, while Ins (1, 3, 4, 5, 6) P5 is not. Also phosphorylates Ins (1, 3, 4) P3 on O-5 and O-6 to form Ins (1, 3, 4, 6) P4, an essential molecule in the hexakisphosphate (InsP6) pathway. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins (1, 3, 4, 5) P4 and Ins (1, 3, 4, 6) P4 to Ins (1, 3, 4) P3, and Ins (1, 3, 4, 5, 6) P5 to Ins (3, 4, 5, 6) P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins (1, 3, 4, 5) P4 and Ins (1, 3, 4, 6) P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q13572

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Inositol-tetrakisphosphate 1-kinase protein (185-414AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:1000-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Signal Transduction

Research Areas: Signal transduction

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