Cusabio Polyclonal Antibodies
INO80 Antibody, FITC conjugated | CSB-PA892466LC01HU
- SKU:
- CSB-PA892466LC01HU
- Availability:
- 3 to 7 Working Days
Description
INO80 Antibody, FITC conjugated | CSB-PA892466LC01HU | Cusabio
INO80 Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: INO80
Aliases: Chromatin-remodeling ATPase INO80 (hINO80) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A), INO80, INO80A, INOC1, KIAA1259
Background: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820) . Binds DNA (PubMed:16298340, PubMed:21303910) . As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910) . Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549) . Involved in UV-damage excision DNA repair (PubMed:20855601) . The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897) . Involved in DNA replication (PubMed:20237820) . Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820) .
Isotype: IgG
Conjugate: FITC
Clonality: Polyclonal
Uniport ID: Q9ULG1
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)
Immunogen Species: Human
Applications: ELISA
Tested Applications: ELISA
Purification Method: >95%, Protein G purified
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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Epigenetics and Nuclear Signaling
Research Areas: Epigenetics & Nuclear Signaling