INO80 Antibody | CSB-PA892466LA01HU

INO80 Antibody | CSB-PA892466LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: INO80

Aliases: Chromatin-remodeling ATPase INO80 (hINO80) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A), INO80, INO80A, INOC1, KIAA1259

Background: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820) . Binds DNA (PubMed:16298340, PubMed:21303910) . As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910) . Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549) . Involved in UV-damage excision DNA repair (PubMed:20855601) . The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897) . Involved in DNA replication (PubMed:20237820) . Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9ULG1

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)

Immunogen Species: Human

Applications: ELISA, WB, IF

Tested Applications: ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IF:1:50-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling