IFNA1 Antibody | CSB-PA365592KA01HU

IFNA1 Antibody | CSB-PA365592KA01HU | Cusabio

IFNA1 Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: IFNA1

Aliases: IFN-α;IFNA1;IFL;IFN;IFN-ALPHA;IFNA13;MGC138207;MGC138505;MGC138507

Background: Interferon-α1 is a member of the Type I IFN family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection. Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis. Other IFN-α1 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity. IFN-α1 binds to the IFN-αR1 and IFN-αR2 heterodimer. Intracellular signaling through the Jak/Stat pathway is best characterized. However, the PI3K, ERK, and p38 kinase pathways are also involved. The antiviral activities of the IFNs have led to their use in treating viral infections. Type I IFNs also appear to have an integral role in several autoimmune diseases.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P01562

Host Species: Rabbit

Species Reactivity: Human, Mouse, Rat

Immunogen: Recombinant protein of human IFN-α

Immunogen Species: Human

Applications: ELISA, WB

Tested Applications: ELISA, WB;WB:1:500-1:2000

Purification Method: Affinity purification

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:2000

Dilution Ratio3:

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Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form: liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Cancer;Immunology