ICK Antibody | CSB-PA891800LA01HU

ICK Antibody | CSB-PA891800LA01HU | Cusabio

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Product Type: Polyclonal Antibody

Target Names: ICK

Aliases: Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (hICK) (Laryngeal cancer kinase 2) (LCK2) (MAK-related kinase) (MRK), ICK, KIAA0936

Background: Required for ciliogenesis (PubMed:24797473) . Phosphorylates KIF3A (By similarity) . Involved in the control of ciliary length (PubMed:24853502) . Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity) . May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity) . Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity) .

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: Q9UPZ9

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC

Tested Applications: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Purification Method: >95%, Protein G purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:500-1:5000

Dilution Ratio3: IHC:1:20-1:200

Dilution Ratio4:

Dilution Ratio5:

Dilution Ratio6:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Epigenetics & Nuclear Signaling;Cell biology