Human lactoferrin | CSB-NP008701h

Human lactoferrin | CSB-NP008701h | Cusabio

Product type: Native Protein

Research areas: Cardiovascular

Target / Protein: Human lactoferrin

Applications: ELISA,WB,SDS-PAGE

Biologically active: Not test

Nature: Native

Protein length: Full length protein

Species of origin: Purified from human milk

Purity: >95%(SDS-PAGE)

Relevance: Lactoferrin is a glycoprotein present in most human mucosal secretions, including human milk. Lactoferrin is bacteriostatic in low iron media and, in some settings, bactericidal. Lactoferrin impairs ability of Shigella flexneri serotype 5 strain M90T to invade HeLa cells. To determine the mechanism by which lactoferrin decreases invasiveness of Shigella organisms, its effect on the major virulence proteins responsible for bacterial uptake by host cells was evaluated. Lactoferrin induced degradation of invasion plasmid antigens IpaB and, to a lesser extent, IpaC, the key proteins responsible for bacteria-directed phagocytosis by mammalian cells.

Storage Buffer: PBS, pH 7.4

Form: Liquid

Stability & Storage: Aliquot and store at -20℃ or -80℃. Avoid repeated freeze/thaw cycles.

Alias: N/A