HSPA8 Monoclonal Antibody | CSB-MA010829A1m

HSPA8 Monoclonal Antibody | CSB-MA010829A1m | Cusabio

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Product Type: Monoclonal Antibody

Target Name: HSPA8

Aliases: Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1) , HSPA8, HSC70 HSP73 HSPA10

Relevance: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP

Isotype: IgG1

Conjugate: Non-conjugated

Clone Number: 6E4D2

Uniport ID: P11142

Alternatives To SCBT: #N/A

Host Species: Mouse

Species Reactivity: Human

Immunogen: Recombinant Human Heat shock cognate 71 kDa protein (2-646AA)

Immunogen Species: Human

Applications: ELISA, WB, IHC, IF, FC

Tested Applications: ELISA, WB, IHC, IF, FC; Recommended dilution: WB: 1:5000-1:32000, IHC: 1:100-1:500, IF: 1:100-1:300, FC: 1:100-1:300

Purification Method: >95%, Protein G purified

Dilution Ratio1: WB:1:5000-1:32000

Dilution Ratio2: IHC:1:100-1:500

Dilution Ratio3: IF:1:100-1:300

Dilution Ratio4: FC:1:100-1:300

Dilution Ratio5:

Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Immunology

Research Areas: Immunology