H3F3A (Ab-79) Antibody | CSB-PA010109OA79nme2HU

H3F3A (Ab-79) Antibody | CSB-PA010109OA79nme2HU | Cusabio

H3F3A (Ab-79) Antibody is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: H3F3A

Aliases: Histone H3.3, H3F3A; H3F3B, H3.3A H3F3; H3.3B

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Isotype: IgG

Conjugate: Non-conjugated

Clonality: Polyclonal

Uniport ID: P84243

Host Species: Rabbit

Species Reactivity: Human, Rat

Immunogen: Peptide sequence around site of Lys (79) derived from Human Histone H3.3

Immunogen Species: Human

Applications: ELISA, WB, ChIP

Tested Applications: ELISA, WB, ChIP; Recommended dilution: WB:1:200-1:2000

Purification Method: Antigen Affinity Purified

Dilution Ratio1: ELISA:1:2000-1:10000

Dilution Ratio2: WB:1:200-1:2000

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Epigenetics and Nuclear Signaling

Research Areas: Epigenetics & Nuclear Signaling