GSDMA Antibody, Biotin conjugated | CSB-PA850415LD01HU

GSDMA Antibody, Biotin conjugated | CSB-PA850415LD01HU | Cusabio

GSDMA Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.

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Product Type: Polyclonal Antibody

Target Names: GSDMA

Aliases: Gasdermin-A (Gasdermin-1), GSDMA, GSDM GSDM1

Background: May promote pyroptosis (Probable) . Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4, 5) -bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216) . The physiological relevance of these observations is unknown (Probable) .

Isotype: IgG

Conjugate: Biotin

Clonality: Polyclonal

Uniport ID: Q96QA5

Host Species: Rabbit

Species Reactivity: Human

Immunogen: Recombinant Human Gasdermin-A protein (64-172AA)

Immunogen Species: Human

Applications: ELISA

Tested Applications: ELISA

Purification Method: >95%, Protein G purified

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Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form: Liquid

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Initial Research Areas: Cell Biology

Research Areas: Cell biology