Cusabio Polyclonal Antibodies
GPR161 Antibody | CSB-PA04114A0Rb
- SKU:
- CSB-PA04114A0Rb
- Availability:
- 3 to 7 Working Days
Description
GPR161 Antibody | CSB-PA04114A0Rb | Cusabio
GPR161 Antibody is Available at Gentaur Genprice with the fastest delivery.
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Product Type: Polyclonal Antibody
Target Names: GPR161
Aliases: G-protein coupled receptor 161 (G-protein coupled receptor RE2), GPR161
Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity) .
Isotype: IgG
Conjugate: Non-conjugated
Clonality: Polyclonal
Uniport ID: Q8N6U8
Host Species: Rabbit
Species Reactivity: Human
Immunogen: Recombinant Human G-protein coupled receptor 161 protein (1-28AA)
Immunogen Species: Human
Applications: ELISA, WB, IF
Tested Applications: ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200
Purification Method: >95%, Protein G purified
Dilution Ratio1: ELISA:1:2000-1:10000
Dilution Ratio2: WB:1:1000-1:5000
Dilution Ratio3: IF:1:50-1:200
Dilution Ratio4:
Dilution Ratio5:
Dilution Ratio6:
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Initial Research Areas: Others
Research Areas: Others